Drug Disposition and Pharmacokinetics: From Principles to Applications by Stephen H. Curry, Robin Whelpton

30th September 2011
Tuesday 10:35 PM
Banaras

Hi! this is an authoritative, comprehensive book on the fate of drug molecules in the body, including implications for pharmacological and clinical effects. The text provides a unique, balanced approach, examining the specific physical and biological factors affecting the absorption, distribution, metabolism and excretion of drugs, together with mathematical assessment of the concentrations in plasma and body fluids. Understanding the equations requires little more than a basic knowledge of algebra, laws of indices and logarithms, and very simple calculus. A companion web site contains additional illustrations, further equations and numerous worked examples.

Download Link:    http://www.fileserve.com/file/AVycScS/0470684461.rar

Drug Disposition and Pharmacokinetics: From Principles to Applications by Stephen H. Curry, Robin Whelpton

This book has its roots in the highly acclaimed book of the same name, written by Stephen Curry nearly thirty years ago, it is essentially a new book having been restructured and largely rewritten. This readable and informative book is an invaluable resource for professionals and students needing to develop a rational approach to the investigation and application of drugs.

Clinical Pharmacokinetics Concepts and Applications by Malcolm Rowland , Thomas Tozer

30th September 2011
Tuesday 10:19 PM
Banaras

Hello, since pharmacokinetics can greatly affect how different patients respond to the same drug, both students and physicians need a basic clinical understanding of this vital area. This textbook covers a tremendous range of topics important in pharmacokinetics and pharmacodynamics.

Download Link:    http://www.easy-share.com/1908354876.html

Clinical Pharmacokinetics Concepts and Applications by Malcolm Rowland , Thomas Tozer

The Third Edition of "Clinical Pharmacokinetics" provides a practical perspective, with these added features: considerations of both stereochemistry and the increasing number of polypeptide and protein drugs being developed; the range and number of problems at the end of each chapter has been expanded; a second color added to make the text more user friendly; and, important equations highlighted by shading.

This book is a very finely crafted comprehensive introduction to pharmacokinetics, with enough pharmacodynamics to give one context. If you are new to PK/PD and need to understand and work with the subject matter this is an excellent starting point and a fine reference. The prose is clear, the organization thoughtful, and the figures and diagrams are masterful - best in class. The authors are both renowned academics with extensive industrial experience. That background shines through in the thoughtful way that topics are motivated and explained. I found the questions useful and thought-provoking. Isn't it the case that the more iron one pumps in the gym, the stronger one is on the playing field?

Applied Clinical Pharmacokinetics by Larry A Bauer

30th September 2009
Tuesday 09:55 PM
Banaras

Hi friends written by a nationally recognized authority in pharmacokinetics, Applied Clinical Pharmacokinetics is full of essential topics for pharmaceutics, pharmacokinetics, therapeutics, and clinical pharmacy courses. It includes information that is critical for practitioners to learn and apply to patient care as well as extensive examples and problems with solutions so readers can master the outlined pharmacokinetic concepts.

Download Link:   http://ifile.it/zaforw8

Applied Clinical Pharmacokinetics by Larry A Bauer

Putting pharmacokinetics into practice, this timely and comprehensive text delivers the latest procedures and data on today’s drugs and patient-specific dosing.

The best guide to pharmacokinetics for real-life pharmacy practice

Ideal for students, pharmacists, and other clinicians who want clear, useful, and up-to-date coverage of the latest standardized techniques and most recent pharmacokinetically monitored drugs

Essential topics for pharmaceutics, pharmacokinetics, therapeutics, and clinical pharmacy courses or can be used in a self-directed manner to self-teach or review important concepts and techniques

Inside: essential information on approaches to drug-dosing and monitoring in individual patients, including the latest data on serum concentrations, written by a nationally recognized leader in pharmacokinetics

Concepts in Clinical Pharmacokinetics by Joseph T. DiPiro, William J. Spruill, William E. Wade, Robert A. Blouin and Jane M. Pruemer

30th September 2009
Tuesday 09:47 PM
Banaras
Hi this is another book provides the basic pharmacokinetic concepts and procedures that are useful in pharmacy, medicine, and other healthcare professions. Topics include pharmacokinetics, half-life, elimination rate, AUC, two-compartment models, drug elimination process, vancomycin, and more.

Download Link:   http://ifile.it/a28b4h5

Concepts in Clinical Pharmacokinetics by Joseph T. DiPiro, William J. Spruill, William E. Wade, Robert A. Blouin and Jane M. Pruemer

This book is organized into 15 lessons. The first 11 lessons provide the basic pharmacokinetic concepts (absorption, distribution, elimination, pharmacodynamics, single- and multiple-dose administrations, protein binding, nonlinearity and model-independent methods), while the last 4 focus on specific drugs that are subject to therapeutic drug monitoring (aminoglycosides, vancomycin, theophylline, digoxin, phenytoin) and discuss case studies. This text is presented very well, its layout is logical and clear, and every lesson builds appropriately upon the preceding ones.

Biopharmaceutics and Pharmacokinetics A Treatise by Brahmankar D M, Jaiswal S B

30th September 2009
Tuesday 09:12 PM
Banaras

Hi friends this book covers the twin disciplines of Biopharmaceutics and Pharmacokinetics have, therefore, been developed with the objective of learning how drugs can be utilized optimally in the treatment of diseases–through design and development of new and better therapeutic moieties, new dosage forms and appropriate dosage regimens. A very good book for undergraduate students of pharmacy.Significant expansion of the chapter on controlled release medication has been made to cover in a broader perspective, the principles employed in the design of such dosage forms, their classification and brief description of the technologies and products delivered by various routes. The concerted attempt was to collectively address the several modern approaches adopted to design the modified drug delivery systems, which is an exciting and highly dynamic area of pharmaceutical research.

Download Link:   http://www.mediafire.com/?qarhwc01636jfqm

Biopharmaceutics and Pharmacokinetics A Treatise by Brahmankar D M, Jaiswal S B

The science and technology associated with pharmacy has progressed enormously over the past few decades. Significant advances in the understanding of diseases have necessitated the need to optimize drug therapy. The concern today is not just to produce elegant and accurate dosage forms but also to ensure that optimum amount of drug reaches the target site at an optimal rate and its concentration is maintained for the entire duration of therapy. A thorough background of the fate of drug after its administration; the rate processes to which it is subjected in the body and its behavior after biotransformation, are thus very essential in addition to the knowledge about its pharmacodynamics.

The chapter on Absorption of Drugs has been dealt with comprehensively as most of its principles also form the basis of drug distribution and elimination. Elaborate treatment of text on Biotransformation of Drugs in chapter 5 is justified since a pharmacy student is well versed with the basic chemistry and enzymology. A brief mention about Bioactivation and Tissue Toxicity has been included at the end of this chapter so that after understanding the mechanisms of drug metabolism, a student will be better placed to appreciate their significance. Prodrugs discussed in chapter 6 give insight into the manner in which chemical formulation techniques can be utilized to overcome some of the inherent biopharmaceutic and pharmacokinetic problems of the active principles. Mathematical treatment of chapters on pharmacokinetics has been kept to at modest level in order not to overburden the students with the complexities of equations and formulae. A brief description of methods usually employed to enhance the bioavailability of a drug from its formulation has been included. In addition to covering various aspects of design of dosage regimens and application of pharmacokinetic principles in clinical situations, the text contains a chapter on Controlled Release Medication to familiarize the students with the principles involved in the design of innovative formulations.

Basic Pharmacokinetics by Sunil S Jambhekar and Philip J Breen

27th September 2009
Tuesday 10:48 PM
Banaras

Hi friends this ia book for undergraduate students of pharmacy. A guide to the study of absorption, distribution, metabolism and elimination of drugs in the body. It provides the reader with a basic understanding of the principles of pharmacokinetics and biopharmaceutics and how these principles, along with the equations presented in each chapter, can be applied to achieve successful drug therapy.

Download Link:  http://ifile.it/wr4cahl

Basic Pharmacokinetics by Sunil S Jambhekar and Philip J Breen

The scope and the intent of this textbook is to provide the reader with a basic intuitive understanding of the principles of pharmacokinetics and biopharmaceutics and how these principles, along with the equations presented in each chapter, can be applied to achieve successful drug therapy. The application of pharmacokinetics principles and equations are illustrated by providing the reader with data available in the literature. As pharmacokinetics is basically mathematical in nature, a chapter has been included to provide the reader with a basic review of the mathematical principles and graphing techniques necessary to understand pharmacokinetics. At the start of each chapter, important objectives are listed to accentuate and identify the key points of the chapter. When an important and clinically applicable equation appears in the text, a paragraph will follow explaining the significance and therapeutic applications of that equation. Additionally, this paragraph includes and explains relevant factors influencing parameters in an equation. When applicable, at the end of an important equation, a general profile illustrating the relationship between the two variables of an equation will be presented. This approach should make the subject matter much more accessible to the student.
Each chapter concludes with related problem sets and problem solving exercises for the student to work through. This should enable the reader to become more adept at solving pharmacokinetic problems arising in drug therapy and understanding the applications and utility of equations in clinical pharmacokinetics and practice. As you can see from the contents, the book is organised into eighteen chapters, the first consists of mathematical principles necessary to understand pharmacokinetics and an overview of the subject matter. The remaining chapters are organised in an order which should be easy for the reader to follow. Clearance and other essential fundamental pharmacokinetic parameters are introduced early in the book as the student will need to apply these concepts in subsequent chapters. A uniform set of notation will be adopted throughout the textbook (a table of which will be at start of the book).

Pharmacokinetic 2nd Edition by Milo Gibaldi and Donald Perrier

23rd June 2011
Friday 04:12 PM

Pharmacokinetics is the study of the time course of drug absorption, distribution, metabolism, and excretion. It also concerns the relationship of these processes to the intensity and time course of pharmacologic (therapeutic and toxicologic) effects of drugs and chemicals. Pharmacokinetics is a quantitative study that requires a preexisting competence in mathematics at least through calculus. It is also a biologic study and can be very useful to the biomedical scientist.

Friends , here is the link of a very good book of pharmacokinetics by Gibaldi.

Download Link:http://www.ziddu.com/download/13345234/GilbadiSecondEdition.pdf.html
Pharmacokinetic by Milo Gibaldi  and Donald Perrier

The most commonly employed approach to the pharmacokinetic characterization of a drug is to represent the body as a system of compartments, even though these compartments usually have no physiologic or anatomic reality, and to assume that the rate of transfer between compartments and the rate of drug elimination from compartments follow first-order or linear kinetics.