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Provides numerous examples and comparisons of modified-release drug delivery systems and highlights in vitro and in vivo studies, manufacturing obstacles, and the patent status associated with over 75 modified-release drug delivery systems.
Modified-Release Drug Delivery Technology by Michael J. Rathbone, Jonathan Hadgraft, Michael S. Roberts
Describing formulation challenges and their solutions in the design, development, and commercialization of modified-release drugs delivery systems, this book contains eighty papers that review recent developments in design and manufacturing techniques. It includes detailed descriptions of extended release drug products for the oral, nasal, ophthalmic, pulmonary, vaginal, dermal and transdermal pathways. With the exception of the final section addressing regulatory issues, each section covers a particular route for drug delivery and opens with an overview of the anatomical, physiological, and pharmaceutical basics of each route before moving on to cover specific technologies.
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